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Blue Gender takes place within the not too distant future in a world the place issues have gone terribly incorrect for humanity. People have been changed on the prime of the meals chain by the Blue, a race of bug-like aliens which have colonized Earth and pushed people apart. An area station, Second Earth, has been constructed as a protected haven for people, with the hope of in the future reclaiming the Earth as soon as extra.
Yuji Kaido was cryogenically frozen, having been affected by a illness referred to as B-Cells. As soon as woke up, he joins a group of troopers which have come to Earth to extract him. Sadly, nothing goes in response to plan as they make their method again to Second Earth.
Yuji must cope with the horrors of preventing a bloody conflict as he and the fighters from Second Earth look to outlive. Will they be capable to win again Earth with out shedding their humanity?